Philip Philipovich, surgeon, reproductive expert and refined borgeois gentleman, makes the grievous error of transplanting a human pituitory gland and testicles into a mongrel he has enticed with a piece of sausage. The dog is unexpectedly transformed into a human, taking on the unprepossessing doggy personality of the deceased donor.
The horrible consequences of the hero's mistake provide a very roadworthy vehicle for social commentary and criticism.